Isolasi Sosial, Kardiovaskular, dan Kematian: Meta-Analisis

Authors

  • Siti Mar’atul Munawaroh Sekolah Tinggi Ilmu Kesehatan Mamba’ul ‘Ulum Surakarta
  • Rina Tri Handayani Sekolah Tinggi Ilmu Kesehatan Mamba’ul ‘Ulum Surakarta
  • Tidy Orchida Sekolah Tinggi Ilmu Kesehatan Mamba’ul ‘Ulum Surakarta
  • Joko Tri Atmojo Sekolah Tinggi Ilmu Kesehatan Mamba’ul ‘Ulum Surakarta
  • Aris Widiyanto Sekolah Tinggi Ilmu Kesehatan Mamba’ul ‘Ulum Surakarta

DOI:

https://doi.org/10.32583/pskm.v14i3.2094

Keywords:

isolasi sosial, kardiovaskular, kematian, meta-analisis

Abstract

Isolasi sosial meningkatkan angka kematian dan kemungkinan besar berdampak pada kesehatan. Penelitian ini bertujuan untuk menganalisis pengaruh isolasi sosial terhadap kardiovaskular dan kematian. Studi meta-analisis ini dilakukan dengan menggunakan flowchart PRISMA dan model PICO yang meliputi: Population: Penduduk dewasa. Intervention: Isolasi sosial. Comparison: Tidak isolasi sosial. Outcome: Kardiovaskular dan Kematian. Pencarian artikel dilakukan melalui database jurnal online meliputi ScienDirect, Scopus, Google Scholar, dan PubMed. Dengan kata kunci “Social Isolation” AND “Cardiovascular” AND “Death” OR “Mortality” AND “adjusted Hazards Ratio”. Penilaian kualitas sebanyak 10 studi primer yang terpublikasi tahun 2012 hingga 2023 dilakukan dengan menggunakan Penilaian Kritis untuk Studi kohor. Data dianalisis menggunakan Review Manager 5.3. Sebanyak 10 artikel studi kohor menyimpulkan bahwa orang dewasa yang mengalami isolasi sosial berisiko untuk mengalami kardiovaskular (aHR= 1.10; CI 95%= 1.07 hingga 1.14; p<0.001) dan kematian (aHR= 1.16; CI 95%= 1.08 hingga 1.18; p= 0.001). Forest plot tersebut juga menunjukkan heteroge­nitas estimasi efek yang rendah antar studi primer I2= 73%; p <0.001. Dengan demikian, per­hitungan rata-rata estimasi efek dilaku­kan dengan pendekatan random effect model. Penelitian ini juga mengindika­sikan tidak adanya bias publikasi.

References

Bauman AE, Reis RS, Sallis JF, Wells JC, Loos RJF, Martin BW, et al. (2012). Correlates of physical activity: why are some people physically active and others not? Lancet Lond Engl. 380(9838):258–71. https://doi.org/10.1016/S0140-6736(12)60735-1

Berkman LF, Melchior M, Chastang JF, Niedhammer I, Leclerc A, Goldberg M. (2004). Social integration and mortality: a prospective study of French employees of Electricity of France-Gas of France: the GAZEL Cohort. Am J Epidemiol. 159(2):167–74. https://doi.org/10.¬1093/-aje/kwh020

Bloom, DE., Cafero ET., Jané-Llopis E., Abrahams-Gessel S., Bloom LR., Fathima S., Feigl AB., Gaziano T., Mowaf M., Pandya A., Prettner K., Rosenberg L., Seligman B., Stein AZ., Weinstein C. (2011). The Global Economic Burden of Noncommunicable Diseases. Geneva: World Economic Forum.

Bu F, Zaninottp P, Fancourt D (2020). Longitudinal associations between loneliness, social isolation and cardiovascular events. Heart. 106:1394–1399. doi:10.1136/heartjnl-2020-316614

Christiansen J, Lund R, Qualter P, Andersen CM, Pedersen SS, Lasgaard M. (2021). Loneliness, Social Isolation, and Chronic Disease Outcomes. Ann Behav Med. 55(3):203-215. doi: 10.1093/abm/kaaa044. PMID: 32865550.

Christakis NA, Fowler JH (2008). The collective dynamics of smoking in a large social network. N Engl J Med. 358(21):2249–58. https://doi.org/10.1056/NEJMsa0706154

Dean M, Raats MM, Grunert KG, Lumbers M, Food in Later Life Team. (2009). Factors influencing eating a varied diet in old age. Public Health Nutr. 12(12):2421–7.

Ellwardt L, van Tilburg T, Aartsen M, Wittek R, Steverink N (2015). Personal networks and mortality risk in older adults: a twenty-year longitudinal study. PLoS One. 10(3):e0116731. doi: 10.1371/journal.pone.0116731.

Elovainio M, Hakulinen C, Pulkki-Råback L, Virtanen M, Josefsson K, Jokela M, et al. (2017). Contribution of risk factors to excess mortality in isolated and lonely individuals: an analysis of data from the UK Biobank cohort study. Lancet Public Health. 2(6):e260–6. https://doi.org/10.1016/S2468-2667 (17)30075-0 PMID: 28626828

Freak-Poli R, Ryan J, Neumann JT, Tonkin A, Reid CM, Woods RL, Nelson M, Stocks N, Berk M, McNeil JJ, Britt C, Owen AJ (2021). Social isolation, social support and loneliness as predictors of cardiovascular disease incidence and mortality. BMC Geriatr. 21(1):711. doi: 10.1186/s12877-021-02602-2.

Golaszewski NM, LaCroix AZ, Godino JG, Allison MA, Manson JE, King JJ, Weitlauf JC, Bea JW, Garcia L, Kroenke CH, Saquib N, Cannell B, Nguyen S, Bellettiere J. (2022). Evaluation of Social Isolation, Loneliness, and Cardiovascular Disease Among Older Women in the US. JAMA Netw Open. 5(2):e2146461. doi: 10.1001/jamanetworkopen.2021.46461.

Hakulinen C, Pulkki-Råback L, Virtanen M, Jokela M, Kivimäki M, Elovainio M. (2018). Social isolation and loneliness as risk factors for myocardial infarction, stroke and mortality: UK Biobank cohort study of 479 054 men and women. Heart. 104(18):1536-1542. doi: 10.1136/heartjnl-2017-312663.

Hawkley LC, Capitanio JP. (2015). Perceived social isolation, evolutionary fitness and health outcomes: a lifespan approach. Philos Trans R Soc Lond B Biol Sci. 370:(1669). https://doi.org/10.1098/rstb. 2014.0114

Holwerda TJ, Beekman AT, Deeg DJ, Stek ML, van Tilburg TG, Visser PJ, Schmand B, Jonker C, Schoevers RA. (2012). Increased risk of mortality associated with social isolation in older men: only when feeling lonely? Results from the Amsterdam Study of the Elderly (AMSTEL). Psychol Med. 42(4):843-53. doi: 10.1017/S0033291711001772

Kraav SL, Awoyemi O, Junttila N, Vornanen R, Kauhanen J, Toikko T, Lehto SM, Hantunen S, Tolmunen T. (2021). The effects of loneliness and social isolation on all-cause, injury, cancer, and CVD mortality in a cohort of middle-aged Finnish men. A prospective study. Aging Ment Health. (12):2219-2228. doi: 10.1080/13607863.2020.1830945

Kobayashi LC, Steptoe A. (2018). Social Isolation, Loneliness, and Health Behaviors at Older Ages: Longitudinal Cohort Study. Ann Behav Med Publ Soc Behav Med. 52(7):582–93. https://doi.org/10. 1093/abm/kax033

Kohl HW, Craig CL, Lambert EV, Inoue S, Alkandari JR, Leetongin G, et al. (2012). The pandemic of physical inactivity: global action for public health. Lancet Lond Engl. 380(9838):294–305. https://doi. org/10.1016/S0140-6736(12)60898-8

Lauder W, Mummery K, Jones M, Caperchione C. (2006). A comparison of health behaviours in lonely and non-lonely populations. Psychol Health Med. 11(2):233–45. https://doi.org/10.1080/ 13548500500266607

Laugesen K, Baggesen LM, Schmidt SAJ, Glymour MM, Lasgaard M, Milstein A, et al. (2018). Social isolation and all-cause mortality: a population-based cohort study in Denmark. Sci Rep. 8(1):4731. https://doi.org/10.1038/s41598-018-22963-w PMID: 29549355

Manemann SM, Chamberlain AM, Roger VL, Griffin JM, Boyd CM, Cudjoe TKM, et al. (2018). Perceived Social Isolation and Outcomes in Patients With Heart Failure. J Am Heart Assoc. 7(11): e008069 https://doi.org/10.1161/JAHA.117.008069

Mendis S, Puska P, Norrving B. (2011). Global Atlas on Cardiovascular Disease Prevention and Control Geneva,. Switzerland: World Health Organization (WHO).

Murti, B. (2023). Penilaian Kualitas Studi Kohor. Universitas Sebelas Maret: Magister Ilmu Kesehatan Masyarakat.

National Academies of Sciences E, Medicine. (2020). Social Isolation and loneli ness in older adults: opportunities for the health care system. Washing ton, DC: The National Academies Press.

Nocon M, Hiemann T, Mu¨ller-Riemenschneider F, Thalau F, Roll S, Willich SN. (2008). Association of physical activity with all-cause and cardiovascular mortality: a systematic review and meta-analysis. Eur J Cardiovasc Prev Rehabil Off J Eur Soc Cardiol Work Groups Epidemiol Prev Card Rehabil Exerc Physiol. 15(3):239–46. https://doi.org/10.1097/HJR.0b013e3282f55e09

Poudel-Tandukar K, Nanri A, Mizoue T, Matsushita Y, Takahashi Y, Noda M, et al. (2011). Social support and suicide in Japanese men and women—the Japan Public Health Center (JPHC)-based prospective study. J Psychiatr Res. 45(12):1545–50. https://doi.org/10.1016/¬j.jpsychires.-2011.07.009

Seeman TE (2000). Health promoting effects of friends and family on health outcomes in older adults. Am J Health Promot AJHP. 14(6):362–70. https://doi.org/10.4278/0890-1171-14.6.362

Shankar A, McMunn A, Banks J, Steptoe A. (2011). Loneliness, social isolation, and behavioral and biological health indicators in older adults. Health Psychol Off J Div Health Psychol Am Psychol Assoc. 30(4):377–85. https://doi.org/10.1037/a0022826

Shiovitz-Ezra S, Litwin H. (2012). Social network type and health-related behaviors: evidence from an American national survey. Soc Sci Med. 75(5):901–4. https://doi.org/10.1016/j.¬socsci¬med.-2012. 04.031

Steptoe A, Shankar A, Demakakos P, Wardle J (2013). Social isolation, loneliness, and all-cause mortality in older men and women. Proc Natl Acad Sci U S A. 110(15):5797-801. doi: 10.1073/pnas.1219686110.

Sterne JA, Herna´n MA, Reeves BC, Savović J, Berkman ND, Viswanathan M, et al. (2016). ROBINS-I: a tool for assessing risk of bias in non-randomised studies of interventions. BMJ. 355:i4919. https:// doi.org/10.1136/bmj.i4919

Tanskanen J, Anttila T. (2016). A Prospective Study of Social Isolation, Loneliness, and Mortality in Finland. Am J Public Health. 106(11):2042–8. https://doi.org/10.2105/AJPH.2016.303431

Umberson D, Montez JK. (2010). Social relationships and health: a flashpoint for health policy. J Health Soc Behav. 51 Suppl:S54–66. https://doi.org/10.1177/0022146510383501

Valtorta NK, Kanaan M, Gilbody S, Ronzi S, Hanratty B. (2016). Loneliness and social isolation as risk factors for coronary heart disease and stroke: sys tematic review and meta-analysis of longitudinal observational studies. Heart. 102(13):1009–16.

Watt RG, Heilmann A, Sabbah W, Newton T, Chandola T, Aida J, et al. (2014). Social relationships and health related behaviors among older US adults. BMC Public Health. 14:533. https://doi.org/10. 1186/1471-2458-14-533

World Health Organization (WHO). (2020). Fact sheets: Cardiovascular diseases (CVDs). Retrieved from: www.who.int/en/news-room/fact-sheets/detail/cardiovascular-diseases-(cvds)

Yang YC, McClintock MK, Kozloski M, Li T. (2013). Social Isolation and Adult Mortality: The Role of Chronic Inflammation and Sex Differences. J Health Soc Behav. 54(2):183–203. https://doi.org/10. 1177/0022146513485244

Yu B, Steptoe A, Chen LJ, Chen YH, Lin CH, Ku PW. (2010). Social Isolation, Loneliness, and All-Cause Mortality in Patients With Cardiovascular Disease: A 10-Year Follow-up Study. Psychosom Med. 82(2):208–14. https://doi.org/10.1097/PSY.0000000000000777

Downloads

Published

2024-01-16

How to Cite

Munawaroh, S. M., Handayani, R. T. ., Orchida, T. ., Atmojo, J. T., & Widiyanto, A. (2024). Isolasi Sosial, Kardiovaskular, dan Kematian: Meta-Analisis. Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal, 14(3), 1143–1154. https://doi.org/10.32583/pskm.v14i3.2094

Issue

Vol. 14 No. 3 (2024): Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal: Juli 2024

Section

article

License

Copyright (c) 2023 Jurnal Ilmiah Permas: Jurnal Ilmiah STIKES Kendal

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.

Most read articles by the same author(s)

1 2 > >>