Efektivitas Oral Care dengan Chlorhexidine dalam Mencegah Ventilator Associated Pneumonia: Systematic Review
DOI:
https://doi.org/10.32583/keperawatan.v15i2.1032Keywords:
chlorhexidine, oral care, VAPAbstract
Ventilator Associated Pneumonia (VAP) merupakan infeksi nosokomial yang didapatkan di rumah sakit khususnya di ruang Intensive Care Unit (ICU) karena penggunaan ventilator. Oral care dengan Chlorhexidine merupakan salah satu yang bermanfaat dalam mencegah terjadinya VAP. Tujuan untuk melakukan tinjauan literatur terkait efektivitas chlorhexidine dalam mencegah VAP. Metode menggunakan tinjauan literatur dengan pendekatan PRISMA. Database yang digunakan dalam seleksi study terdiri dari PROQUEST, Pubmed, Science Direct dan Ebscohost dengan menggunakan kata kunci Ventilator Associated Pneumonia, Oral care dan Chlorhexidine. Total artikel yang ditemukan sejumlah 709 artikel dari tahun 2017-2022 dengan dilakukan proses eliminasi disesuaikan dengan kriteria inklusi yaitu teks lengkap, penelitian eksperimen, menggunakan subyek manusia, dan berbahasa inggris. Berdasarakan proses eliminasi didapatakan 7 artikel terpilih dari 709 artikel yang menyebutkan bahwa oral care dengan chlorhexidine 2% tiga kali sehari efektif dalam mencegah terjafinya VAP.
References
Akdogan, O., Ersoy, Y., Kuzucu, C., Gedik, E., Togal, T., & Yetkin, F. (2017). Assessment of the effectiveness of a ventilator associated pneumonia prevention bundle that contains endotracheal tube with subglottic drainage and cuff pressure monitorization. Brazilian Journal of Infectious Diseases, 21(3), 276–281. https://doi.org/10.1016/j.bjid.2017.01.002
Ali Karimpour, H., Hematpour, B., Mohammadi, S., Aminisaman, J., Mirzaei, M., Morteza Karimian, S., Mumtaz, F., & Kaviannejad, R. (2020). Effect of Nebulized Eucalyptus for Preventing Ventilator-associated Pneumonia in Patients Under Mechanical Ventilation: A Randomized Double Blind Clinical Trial. Alternative Therapies in Health and Medicine, 26(S2), 126–130.
Burja, S., Belec, T., Bizjak, N., Mori, J., Markota, A., & Sinkovič, A. (2018). Efficacy of a bundle approach in preventing the incidence of ventilator associated pneumonia (VAP). Bosnian Journal of Basic Medical Sciences, 18(1), 105–109. https://doi.org/10.17305/bjbms.2017.2278
Chacko, R., Rajan, A., Lionel, P., Thilagavathi, M., Yadav, B., & Premkumar, J. (2017). Oral decontamination techniques and ventilator-associated pneumonia. British Journal of Nursing, 26(11), 594–599. https://doi.org/10.12968/bjon.2017.26.11.594
Choi, M. I., Han, S. Y., Jeon, H. S., Choi, E. S., Won, S. E., Lee, Y. J., Baek, C. Y., & Mun, S. J. (2022). The Effect of Professional Oral Care on the Oral Health Status of Critical Trauma Patients Using Ventilators. International Journal of Environmental Research and Public Health, 19(10). https://doi.org/10.3390/ijerph19106197
Da Collina, G. A., Tempestini-Horliana, A. C. R., da Silva, D. de F. T., Longo, P. L., Makabe, M. L. F., & Pavani, C. (2017). Oral hygiene in intensive care unit patients with photodynamic therapy: Study protocol for randomised controlled trial. Trials, 18(1), 1–10. https://doi.org/10.1186/s13063-017-2133-y
Fernanda, C., Vidal, D. L., Karla, A., Vidal, D. L., Gildo, J., Monteiro, D. M., Cavalcanti, A., Paula, A., Henriques, T., Oliveira, M., Godoy, M., Coutinho, M., Sobral, P. D., Vilela, C. Â., Gomes, B., Leandro, M. A., & Montarroyos, U. (2017). Impact of oral hygiene involving toothbrushing versus chlorhexidine in the prevention of ventilator-associated pneumonia : a randomized study. 1–10. https://doi.org/10.1186/s12879-017-2188-0
Hayashida, S., Funahara, M., Sekino, M., Yamaguchi, N., Kosai, K., Yanamoto, S., Yanagihara, K., & Umeda, M. (2016). The effect of tooth brushing, irrigation, and topical tetracycline administration on the reduction of oral bacteria in mechanically ventilated patients: A preliminary study. BMC Oral Health, 16(1), 1–7. https://doi.org/10.1186/S12903-016-0224-X
Jaillette, E., Girault, C., Brunin, G., Zerimech, F., Behal, H., Chiche, A., Broucqsault-Dedrie, C., Fayolle, C., Minacori, F., Alves, I., Barrailler, S., Labreuche, J., Robriquet, L., Tamion, F., Delaporte, E., Thellier, D., Delcourte, C., Duhamel, A., & Nseir, S. (2017). Impact of tapered-cuff tracheal tube on microaspiration of gastric contents in intubated critically ill patients: a multicenter cluster-randomized cross-over controlled trial. Intensive Care Medicine, 43(11), 1562–1571. https://doi.org/10.1007/s00134-017-4736-x
Joseph Loscalzo. (2017). Pulmonologi dan Penyakit Kritis (2nd ed.). EGC.
Kes, D., Aydin Yildirim, T., Kuru, C., Pazarlioglu, F., Ciftci, T., & Ozdemir, M. (2021). Effect of 0.12% Chlorhexidine Use for Oral Care on Ventilator-Associated Respiratory Infections: A Randomized Controlled Trial. Journal of Trauma Nursing, 28(4), 228–234. https://doi.org/10.1097/JTN.0000000000000590
LI, D. F., SHI, C. X., ZHAO, L., SHI, F. Z., JIANG, M. L., & KANG, W. Q. (2021). Prevention of neonatal ventilator-associated pneumonia through oral care with the combined use of colostrum and sodium bicarbonate. European Review for Medical and Pharmacological Sciences, 25(5), 2361–2366. https://doi.org/10.26355/eurrev_202103_25275
Mahmoodpoor, A., Hamishehkar, H., Hamidi, M., Shadvar, K., Sanaie, S., Golzari, S. E., Khan, Z. H., & Nader, N. D. (2017). A prospective randomized trial of tapered-cuff endotracheal tubes with intermittent subglottic suctioning in preventing ventilator-associated pneumonia in critically ill patients. Journal of Critical Care, 38, 152–156. https://doi.org/10.1016/j.jcrc.2016.11.007
Mahmoodpoor, A., Sanaie, S., Ph, D., Parthvi, R., Shadvar, K., Hamishekar, H., Ph, D., Iranpour, A., Nuri, H., Rahnemayan, S., Nader, N. D., & Ph, D. (2020). A clinical trial of silver-coated and tapered cuff plus supraglottic suctioning endotracheal tubes in preventing ventilator- associated pneumonia. Journal of Critical Care, 56, 171–176. https://doi.org/10.1016/j.jcrc.2019.12.024
Morton, P. G. (2016). Keperawatan Kritis: Pendekatan Asuhan Holistik (vol 1).
Patricia Gonce Morton; Dorrie Fontaine; Carolyn M. Hudak; Barbara M. Gallo. (2018). Keperawatan Kritis (8th ed.). EGC.
Rabello, F., Araújo, V. E., & Magalhães, S. M. S. (2018). Effectiveness of oral chlorhexidine for the prevention of nosocomial pneumonia and ventilator-associated pneumonia in intensive care units: Overview of systematic reviews. International Journal of Dental Hygiene, 16(4), 441–449. https://doi.org/10.1111/idh.12336
Rahman, D., Huriani, E., & Julita, E. (2017). Kejadian Ventilator Associated Pneumonia (VAP) pada Klien dengan Ventilasi Mekanik Menggunakan Indikator Clinical Pulmonary Infection Score (CPIS). Jurnal Ners, 6(2), 126–135. https://doi.org/10.20473/jn.v6i2.3975
Ramadhan, H. N. (2019). Pelaksanaan Pencegahan dan Pengendalian Ventilator Associated Pneumonia (VAP) di Ruang ICU. The Journal of Hospital Accreditation, 1(1), 3–8. https://doi.org/10.35727/jha.v1i1.11
Reis, M. A. O., de Almeida, M. C. S., Escudero, D., & Medeiros, E. A. (2022). Chlorhexidine gluconate bathing of adult patients in intensive care units in São Paulo, Brazil: Impact on the incidence of healthcare-associated infection. Brazilian Journal of Infectious Diseases, 26(1), 1–6. https://doi.org/10.1016/j.bjid.2021.101666
Sanaie, S., Rahnemayan, S., Azizi, S., Saghaleini, S. H., Ghamari, A. A., Ghojazadeh, M., & Mahmoodpoor, A. (2022). Comparison of subglottic vs. non-subglottic secretion drainage in prevention of Ventilator Associated Pneumonia: A systematic review and meta-analysis. Trends in Anaesthesia and Critical Care, 43, 23–29. https://doi.org/10.1016/j.tacc.2022.02.002
Stokker, J., Karami, M., Hoek, R., Gommers, D., & van der Eerden, M. (2020). Effect of adjunctive tobramycin inhalation versus placebo on early clinical response in the treatment of ventilator-associated pneumonia: the VAPORISE randomized-controlled trial. Intensive Care Medicine, 46(3), 546–548. https://doi.org/10.1007/s00134-019-05914-5
Su, K. C., Kou, Y. R., Lin, F. C., Wu, C. H., Feng, J. Y., Huang, S. F., Shiung, T. F., Chung, K. C., Tung, Y. H., Yang, K. Y., & Chang, S. C. (2017). A simplified prevention bundle with dual hand hygiene audit reduces early-onset ventilator-associated pneumonia in cardiovascular surgery units: An interrupted time-series analysis. PLoS ONE, 12(8), 1–19. https://doi.org/10.1371/journal.pone.0182252
Villar, C. C., Pannuti, C. M., Nery, D. M., Morillo, C. M. R., Carmona, M. J. C., & Romito, G. A. (2016). Effectiveness of intraoral chlorhexidine protocols in the prevention of ventilator-associated pneumonia: Meta-analysis and systematic review. Respiratory Care, 61(9), 1245–1259. https://doi.org/10.4187/respcare.04610
Wang, R., Zhen, X., Yang, B.-Y., Guo, X.-Z., Zeng, X., & Deng, C.-Y. (2015). Subglottic secretion drainage for preventing ventilator associated pneumonia: A meta-analysis. Chinese Nursing Research, 2(2–3), 55–60. https://doi.org/10.1016/j.cnre.2015.03.001
Ward, J. P. (2015). The Respiratory System at a Glance (J. W. & Sons (ed.); 4th ed.). West Sussex.
Zand, F., Zahed, L., Mansouri, P., Dehghanrad, F., Bahrani, M., & Ghorbani, M. (2017). The effects of oral rinse with 0 . 2 % and 2 % chlorhexidine on oropharyngeal colonization and ventilator associated pneumonia in adults ’ intensive care units. Journal of Critical Care, 40, 318–322. https://doi.org/10.1016/j.jcrc.2017.02.029.
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