Hubungan Demografi (Pendidikan, Pekerjaan) dan Faktor Determinan (Pola Makan, Genetik, Obat-Obatan, Psikososial) Pasien Endometriosis terhadap Keberhasilan Kehamilan Program Bayi Tabung
DOI:
https://doi.org/10.32583/keperawatan.v16i4.2026Keywords:
demografi, endometriosis, faktor determinan, keberhasilan kehamilan program bayi tabungAbstract
Endometriosis ditandai adanya endometrium di luar rongga rahim dan infiltrasi jaringan ektopik, menyebabkan peradangan, nyeri, dan infertilitas. Keadaan infertilitas yang berkaitan dengan endometriosis terutama pada stadium III dan IV sering kali memerlukan Assisted Reproductive Technologies (ART) untuk dapat mencapai kehamilan, salah satunya adalah Fertilisasi in Vitro (FIV) / bayi tabung. Penelitian ini bertujuan untuk Menganalisa Hubungan Demografi (Pendidikan, Pekerjaan) Dan Faktor Determinan (Pola Makan, Genetik, Obat-Obatan, Psikososial) Pasien Endometriosis Terhadap Keberhasilan Kehamilan Program Bayi Tabung. Desain penelitian yang digunakan adalah penelitian mix method. Metode pengambilan sampel dengan purposive sampling dengan kriteria inklusi pasien di Klinik Yasmin yang mengalami endometriosis dan sedang melakukan program FIV yang telah mencapai embrio transfer berjumlah sebanyak 51 orang. Metode pengumpulan data menggunakan The explanatory sequential design dengan instrumen Form FFQ, hasil analisa pemeriksaan USG dan wawancara mendalam. Proses analisis data menggunakan analisis univariat dan analisis bivariat dengan uji korelasi Chi square, analisa kualitatif dengan metode Coalllizi’s. Hasil penelitian menunjukkan hasil uji statistik diperoleh nilai p < 0.05, maka terdapat hubungan Demografi (Pendidikan, Pekerjaan) Dan Faktor Determinan (Pola Makan, Genetik, Obat-Obatan) Pasien Endometriosis Terhadap Keberhasilan Kehamilan Program Bayi Tabung. Hasil kualitatif ditemukan 3 tema utama yang terdiri dari domain psiko-emosional, domain psikososial dan domain suport keluarga. Hasil penelitian dapat menjadi rujukan bagi perawat dalam perawatan Assisted Reproductive Technologies (ART) atau program pelayanan infertilitas sehingga keberhasilan program bayi tabung dapat ditingkatkan.
References
Bell, R. J., Robinson, P. J., Skiba, M. A., Islam, R. M., Hemachandra, C., & Davis, S. R. (2023). The impact of endometriosis on work ability in young Australian women. Australian and New Zealand Journal of Obstetrics and Gynaecology, 63(4), 556–563. https://doi.org/10.1111/ajo.13683
Dhyani, I., Yukhi, K., Made, O., (2020). Hubungan Antara Faktor-Faktor Penyebab Infertilitas Terhadap Tingkat Keberhasilan IVF-ICSI Di RSIA Puri Bunda Denpasar Pada Tahun 2017. Jurnal Medika Udayana (JMU), Vol 9 No.5, 1-7. DOI: https://doi.org/10.33992/jik.v10i1.1557
Elbasueny, B., Geerts, M., Yang, E. C., Allaire, C., Yong, P. J., & Bedaiwy, M. A. (2023). Medical treatments of endometriosis: A review. In Reproductive and Developmental Medicine (Vol. 7, Issue 3, pp. 166–179). Lippincott Williams and Wilkins. https://doi.org/10.1097/RD9.0000000000000053
Filby, C. E., Rombauts, L., Montgomery, G. W., Giudice, L. C., & Gargett, C. E. (2020). Cellular Origins of Endometriosis: Towards Novel Diagnostics and Therapeutics. Seminars in Reproductive Medicine, 38(02/03), 201-215. https://doi.org/10.1055/s-0040-1713429
Goodwin, E., Abreu do Valle, H., Nitschke, A., Puyat, J., Yong, P. J., & Hanley, G. E. (2023). The Association Between Endometriosis Treatments and Depression and/or Anxiety in a Population-Based Pathologically Confirmed Cohort of People with Endometriosis. Women’s Health Reports, 4(1), 551–561. https://doi.org/10.1089/whr.2023.0068
Hamsah dan Nasrudin. (2019). Karakteristik Pasangan Infertil di BLU RS Dr. Wahidin Sudirohusodo Makassar. Green Medical Journal, vol. 1, no. 1, 2019, pp. 1-14, https://doi.org/10.33096/gmj.v1i1.15.
Indarwati, I., Hastuti, U.R., & Dewi, Y.L. (2017). Analysis of Factors Influencing Female Infertility. Journal of Maternal and Child Health 2(2): 150-161 https://doi.org/10.26911/thejmch.2017.02.02.06
Invitti, A. L., & Demetriou, L. (2023). Editorial: The impact of endometriosis. In Frontiers in Global Women’s Health (Vol. 4). Frontiers Media S.A. https://doi.org/10.3389/fgwh.2023.1190974
Iordăchescu, D. A., Paica, C. I., Boca, A. E., Gică, C., Panaitescu, A. M., Peltecu, G., Veduță, A., & Gică, N. (2021). Anxiety, difficulties, and coping of infertile women. Healthcare (Switzerland), 9(4). https://doi.org/10.3390/healthcare9040466
Jamhariyah, J., Dian, D., & Sasmito, L. (2022). Obesitas Dengan Kejadian Infertilitas Pada Wanita Usia Subur. Healthy : Jurnal Inovasi Riset Ilmu Kesehatan, 1(2), 121–131. https://doi.org/10.51878/healthy.v1i2.1246
Kamaryati, Ni & Malathum, Porntip. (2020). Family Support: A Concept Analysis. 403-411. https://www.researchgate.net/publication/343253776
Khan, S., & Lee, C. L. (2021). Treating Deep Endometriosis in Infertile Patients before Assisted Reproductive Technology. Gynecology and minimally invasive therapy, 10(4), 197–202. https://doi.org/10.4103/GMIT.GMIT_154_20
Koser, K. (2020). Fertility Counseling With Couples: A Theoretical Approach. The Family Journal, 28(1), 25-32. https://doi.org/10.1177/1066480719887498
Kurniawan dkk. (2020). Hubungan Kadar β-hCG 12 Hari Pasca Transfer Embryo dengan Luaran Kehamilan. Jurnal Kesehatan Reproduksi, 7(1), 1-5. https://doi.org/10.22146/jkr.53479
Lalami, I., Abo, C., Borghese, B., Chapron, C., & Vaiman, D. (2021). Genomics of endometriosis: From genome wide association studies to exome sequencing. In International Journal of Molecular Sciences (Vol. 22, Issue 14). MDPI. https://doi.org/10.3390/ijms22147297
Luqyana, S., & Moekroni, R. (2020). Diagnosis Dan Tatalaksana Terbaru Endometriosis. JIMKI: Jurnal Ilmiah Mahasiswa Kedokteran Indonesia, 7(2), 67-75. https://doi.org/10.53366/jimki.v7i2.66
Marlinda, M., Afiyati, Y., & Budiati, T. (2018). Asuhan Keperawatan Pada Klien Dengan Kista Endometriosis Menggunakan Pendekatan Teori Comfort Dan Loss & Grief. Jurnal Kesehatan Panca Bhakti Lampung, 6(2), 117. https://doi.org/10.47218/jkpbl.v6i2.48
Matasariu, R. D., Mihaila, A., Iacob, M., Dumitrascu, I., Onofriescu, M., Crumpei Tanasa, I., & Vulpoi, C. (2017). Psycho-social aspects of quality of life in women with endometriosis. In Acta Endocrinologica (Vol. 13, Issue 3, pp. 334–339). Acta Endocrinologica Foundation. https://doi.org/10.4183/aeb.2017.334
Márki, G., Vásárhelyi, D., Rigó, A., Kaló, Z., Ács, N., & Bokor, A. (2022). Challenges of and possible solutions for living with endometriosis: a qualitative study. BMC Women’s Health, 22(1). https://doi.org/10.1186/s12905-022-01603-6
Mu, F., Rich-Edwards, J., Rimm, E. B., Spiegelman, D., Forman, J. P., & Missmer, S. A. (2017). Association between Endometriosis and Hypercholesterolemia or Hypertension. Hypertension, 70(1), 59–65. https://doi.org/10.1161/Hypertensionaha.117.09056
Nap, A., & de Roos, N. (2022). Endometriosis and the effects of dietary interventions: what are we looking for? Reproduction and Fertility, 3(2), C14–C22. https://doi.org/10.1530/RAF-21-0110
Nurhadhani dan Suzanna. (2022). Penerimaan Diri Wanita Infertilitas. Jurnal Psikologi Terapan (JPT), Vol 3, No.2 , 1-10.https://doi.org/10.29103/jpt.v3i2.8876
Pickett, C., Foster, W. G., & Agarwal, S. (2023). Current endometriosis care and opportunities for improvement. Reproduction & fertility, 4(3), e220091. Advance online publication. https://doi.org/10.1530/RAF-22-0091
Putri, P.M. (2021). Karakteristik Pasien Yang Menjalani Bayi Tabung Dengan Protokol Antagonis Di Klinik Bayi Tabung Rumah Sakit Umum Pusat Sanglah Tahun 2014 – 2017. E-Jurnal Medika Udayana.
René, C., Landry, I., & de Montigny, F. (2022). Couples’ experiences of pregnancy resulting from assisted reproductive technologies: A qualitative meta-synthesis. In International Journal of Nursing Studies Advances (Vol. 4). Elsevier B.V. https://doi.org/10.1016/j.ijnsa.2021.100059
Rooney, K. L., & Domar, A. D. (2018). The relationship between stress and infertility. Dialogues in Clinical Neuroscience, 20(1), 41–47. https://doi.org/10.31887/dcns.2018.20.1/klrooney
Shi, J., Tan, X., Feng, G., Zhuo, Y., Jiang, Z., Banda, S., Wang, L., Zheng, W., Chen, L., Yu, D., & Guo, C. (2023). Research advances in drug therapy of endometriosis. In Frontiers in Pharmacology (Vol. 14). Frontiers Media SA. https://doi.org/10.3389/fphar.2023.1199010
Škegro, B., Bjedov, S., Mikuš, M., Mustač, F., Lešin, J., Matijević, V., Ćorić, M., Elveđi Gašparović, V., Medić, F., & Sokol Karadjole, V. (2021). Endometriosis, Pain and Mental Health. Psychiatria Danubina, 33(Suppl 4), 632–636.
Smolarz, B., Szyłło, K., & Romanowicz, H. (2021). Endometriosis: Epidemiology, classification, pathogenesis, treatment and genetics (review of literature). International Journal of Molecular Sciences, 22(19). https://doi.org/10.3390/ijms221910554
Somigliana, E., Piani, L. L., Paffoni, A., Salmeri, N., Orsi, M., Benaglia, L., Vercellini, P., & Vigano’, P. (2023). Endometriosis and IVF treatment outcomes: unpacking the process. In Reproductive Biology and Endocrinology (Vol. 21, Issue 1). BioMed Central Ltd. https://doi.org/10.1186/s12958-023-01157-8
Suryoningrat dkk. (2021). Apakah Endometriosis Mempengaruhi Kualitas Embryo pada Pasien Invitro Fertilization?. Jurnal Kesehatan Reproduksi 8 (1), 1-5. https://doi.org/10.22146/jkr.63039
Szypłowska, M., Tarkowski, R., & Kułak, K. (2023). The impact of endometriosis on depressive and anxiety symptoms and quality of life: a systematic review. In Frontiers in Public Health (Vol. 11). Frontiers Media SA. https://doi.org/10.3389/fpubh.2023.1230303Taylor HS, P. L. (2020). Endometriosis. Philadelpia: Wolters Kluwer.
Vennberg Karlsson, J., Patel, H., & Premberg, A. (2020). Experiences of health after dietary changes in endometriosis: A qualitative interview study. BMJ Open, 10(2). https://doi.org/10.1136/bmjopen-2019-032321
Wulandari, D.R., Handono, B., Rachmawati, A., & Hidayat, D.R. (2020). Luaran Kehamilan pada Pasien dengan Infertilitas Berkaitan dengan Endometriosis, Infertilitas karena Faktor Tuba, dan Unexplained Infertility, setelah Menjalani Prosedur IVF / ICSI di Klinik Aster RSUP Dr. Hasan Sadikin Bandung. Indonesian Journal of Obstetrics & Gynecology Science.
Yang, J., Wen, Y., Li, D., Hou, X., Peng, B., & Wang, Z. (2023). Retrospective analysis of the endometrial preparation protocols for frozen-thawed embryo transfer cycles in women with endometriosis. Reproductive Biology and Endocrinology, 21(1). https://doi.org/10.1186/s12958-023-01132-3
Zandi, N., Behboodi Moghadam, Z., Hossein Rashidi, B., Namazi, M., & Haghani, S. (2023). Reproductive health of women with endometriosis: an improving educational intervention based on the planned behavior theory. Middle East Fertility Society Journal, 28(1). https://doi.org/10.1186/s43043-023-00129-7
Zondervan, K. T., Becker, C. M., & Missmer, S. A. (2020). Endometriosis. New England Journal of Medicine, 382(13), 1244–1256. https://doi.org/10.1056/NEJMra1810764
Zieliński, K., Drabczyk, D., Kunicki, M., Drzyzga, D., Kloska, A., & Rumiński, J. (2023). Evaluating the risk of endometriosis based on patients’ self-assessment questionnaires. Reproductive Biology and Endocrinology, 21(1). https://doi.org/10.1186/s12958-023-01156-9.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2024 Jurnal Keperawatan
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.